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Some relevant outcomes that can quantify malnutrition could include multidimensional assessment tools such as the Geriatric Nutritional Risk Index (GNRI) or the Mini Nutritional Assessment (MNA)

Severe gastrointestinal disease, particularly gastroparesis, may alter both efficacy and tolerability and requires careful consideration

doi: 10.1056/NEJMoa1607141 9 ArodaVR