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Moreover, coexisting diabetes, a common inclusion criterion in earlier GLP-1RA studies, may itself confound neuroprotective effects through independent metabolic and vascular improvements

Slowed Gastric Emptying Semaglutide slows down the emptying of food from the stomach into the small intestine

For example, administration of the NMDA receptor antagonist memantine induces anorexia and weight loss in rodents and modifies their food preferences [119]

Diarrhea: While less common than constipation, diarrhea can occur as a side effect

Medical Supervision and Monitoring for Optimal Outcomes If you have had your gallbladder removed and want to try semaglutide, a thorough pre-treatment evaluation by your primary care doctor or a weight loss specialist is essential