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NOTE: patient should not get pregnant on ERAs because of teratogenicity
Translation into the clinic requires that sound waves either penetrate the human skull (which is considerably denser than in rodent models) or bypass the bone 52,53
This renal excretion is relevant when considering individual patient factors such as renal function, as impaired kidney function can affect the clearance of anticonvulsants and influence their duration of action
That doesnt change the core principle
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