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Incretins significantly influence the regulation of numerous physiological processes in different organs

This model was then extrapolated to three specific age subgroups, i.e., children (1012 years), early adolescents (1215 years), and adolescents (1518 years)

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For Study 3, the primary efficacy parameters were mean percent change in body weight from randomization (Week 0) to Week 72 and the percentage of patients achieving 5% weight reduction from randomization (Week 0) to Week 72