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Routine monitoring of serum calcitonin or using thyroid ultrasound is of uncertain value for early detection of MTC in patients treated with RYBELSUS Important Safety Information for RYBELSUS WARNING: RISK OF THYROID C-CELL TUMORS In rodents, semaglutide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures

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Besides, Exendin-4 could promote the polarization of bone marrow-derived macrophages into M2 subtype (4.2 g/kg/day) (31)

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Suppresses Glucagon Release: GLP-1 inhibits the secretion of glucagon from pancreatic alpha cells

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