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Tirzepatide: A novel cardiovascular protective agent in type 2 diabetes mellitus and obesity

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The body cleaves off the cyanide group during metabolism and converts cyanocobalamin into its active coenzyme forms, methylcobalamin and adenosylcobalamin, which then participate in critical biochemical reactions throughout the body

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This changes the charge of the amino acid, which can alter the three-dimensional structure of the peptide and reduce its biological activity
