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Description
doi:10.3748/wjg.v26.i21.2740 23
While all GLP-1 medications work by mimicking the natural hormone glucagon-like peptide-1 to help regulate appetite and digestion, there are some key differences between them
Dose escalation schedules are brand-specificfor example, Wegovy (semaglutide for weight management) follows a weekly titration schedule, while Saxenda (liraglutide for weight management) has a daily titration protocol
The pituitary gland is located outside the bloodbrain barrier and expresses GLP-1 R in both rats and humans [39]
People who are unable to tolerate higher doses but still experience meaningful benefits when experimenting with lower off label doses
