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Some patients feel the effect almost immediately after starting the medication, says Jessica Bartfield, M.D., an obesity medicine physician and associate professor at Wake Forest University School of Medicine who specializes in medical weight management

Later that year, however, a new observational study published in JAMA Network Open reignited the debate around the safety of the class, prompting the FDA to take another look

Arakawa M, Mita T, Azuma K et al (2010) Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like

This process both washes the solution and enhances its stability