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Figure: White exudate and cobblestone appearance of mucosa of the left colon consistent with ischemic colitis Figure: Colonic mucosa showing ulceration, withering crypts, crypt dropout, and lamina propria and submucosal hyalinization consistent with ischemic colitis (10X) Disclosures: Nancy Mayer indicated no relevant financial relationships

Additionally, clinical trials showed Wegovy patients lost 1518% of their body weight

Large outcome trials with GLP-1 receptor agonists show reductions in major adverse cardiovascular events for several agents, including semaglutide in selected populations

In most cases, patients do not experience uncontrollable hunger

Tirzepatide (Mounjaro, Zepbound) is usually prescribed alongside eating nutritious foods to support weight loss