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GLP-1 RAs are chronic medications for long-term use

Another study found that liraglutide decreased diabetic neuropathy-induced microglial cell activation in the cerebral cortex and thalamus of rats by reducing the expression of the NLR family pyrin domain containing 3 (NLRP3) protein in brain microglia [47]
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However, most pivotal trials were designed to evaluate: Weight loss Glycaemic control Cardiovascular outcomes Safety and tolerability Micronutrient status was rarely a primary or secondary endpoint
doi: 10.1186/alzrt174 [DOI] [PMC free article] [PubMed] [Google Scholar] 75.Gejl M, Brock B, Egefjord L, Vang K, Rungby J, Gjedde A
