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Description
doi: 10.1155/2022/6813017

Study Selection We selected pharmacokinetic studies of any injectable GLP1RA given with an oral medication, and product prescribing sheets reporting data without access to the original study

Chen S, Liu AR, An FM, Yao WB, Gao XD

Studies have shown that activation of the GLP1 receptor downregulates the expression of NADPH oxidase NOX3 and mitochondrial superoxide dismutase SOD2, thereby reducing ROS levels, blocking the oxidative stress-induced upregulation of Beclin1 expression and increased LC3-II/I ratio, and delaying autophagosome formation [57]

Mima, H
