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Table 2) [13]

It belongs to a class of medications known as dual glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonists

In light of these promising findings, a critical question arises: Can onceweekly semaglutide at this dose level not only facilitate weight loss but also alleviate symptoms, reduce physical limitations, and enhance exercise capacity in patients afflicted by the challenging combination of HFpEF and obesity

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Those with significant medical co-morbidities, prior CSF diversion procedures, neurovascular stenting or optic nerve sheath fenestration, those currently using GLP-1 receptor agonists, dipeptidyl peptidase-4 (DPP-4) inhibitors or taking drugs that could reduce ICP were excluded