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Griffonia : Griffonia (Griffonia simplicifolia) a plant native to Africa, is renowned for its high content of 5-HTP (5-hydroxytryptophane), a direct precursor of serotonin, commonly referred to as the "happiness hormone." Griffonia is particularly valued for its ability to enhance brain activity and support emotional well-being

By exploring human studies and mechanistic insights, this review underscores irisins potential to address global health challenges, such as obesity and type 2 diabetes, while advancing strategies for personalized exercise interventions.

It has been thought that incretin signaling prevents arteriosclerosis, and very recently anti-arteriosclerotic effects through GLP-1 receptor were finally demonstrated in clinical human study

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