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This unimolecular dual incretin, which was derived from a mixed sequence of GLP- 1 and GIP, showed improved antihyperglycemic and insulinotropic activity compared to selective GLP- 1 agonists

Current treatments include a range of medical and surgical approaches, such as topical and systemic antibiotics, retinoids, hormonal therapies, and biologics like TNF and IL-17 inhibitors (e.g., adalimumab, secukinumab, bimekizumab) [6]

After screening titles and abstracts, 64 studies were selected for full-text review, and 41 articles were ultimately included in this review, including 12 randomized controlled trials, 16 observational studies, and 13 mechanistic or preclinical studies

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