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Like most medicines, Rybelsus can cause some side effects, and the ones most commonly reported include nausea, diarrhoea, abdominal discomfort, and decreased appetite

Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes

B12 absorption can decrease during semaglutide therapy due to slower gastric emptying

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Furthermore, the expanding investigation of semaglutide in Alzheimer's disease through the EVOKE Plus trial program, anticipated to report results by 2026 and 2027, represents a potentially enormous new indication that could add tens of millions of patients to the addressable treatment population globally, with corresponding API volume requirements that dwarf those of the existing obesity and diabetes indications