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Purpose-built for physicians Human, exendin-based GLP-1 receptor agonists similarly reduce CV, renal risk in diabetes A pooled study assessing trials of eight GLP-1 receptor agonists showed all reduce risk for a combined endpoint of major adverse cardiovascular events, regardless of structural homology to human GLP-1, as well as individual CV components

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Herlev og Gentofte Hospital Steno Diabetes Center Copenhagen Department of Biomedical Sciences Mats Christian Hjbjerg Lassen, MD To view or add a comment, sign in Moderate-to-Vigorous Physical Activity and Cardiovascular Outcomes in Genotype-Positive, Phenotype-Negative Cardiomyopathy Carriers In a large prospective cohort from the UK Biobank including 84,699 individuals, of whom 3,979 were genotype-positive and phenotype-negative (G+P) carriers of cardiomyopathy-associated variants, objectively measured moderate-to-vigorous physical activity (MVPA) was consistently associated with meaningful cardiovascular benefit