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GLP-1s are linked to a higher risk for osteoporosis, gout, and osteomalacia in people with type 2 diabetes and obesity, new research suggests, though an additional study also points to better orthopedic outcomes in semaglutide users.
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In the subgroup analyses, human GLP-1 RAs, but not nonhuman GLP-1 RAs, reduced the risk of MACE in patients with HF (p interaction = 0.11)
