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The landmark SADISLEEVE randomised controlled trial (Robert et al., The Lancet, 2025) demonstrated SADI produced superior weight loss versus Roux-en-Y gastric bypass at 2-year follow-up with a similar safety profile
Medically reviewed by Emily Bigby, MD, Physician at Ivm Health Medical Disclaimer: This content is for informational and educational purposes only and is not intended as medical advice, diagnosis, or treatment
95% CI, 0.18-0.74), pancreatic cancer (HR = 0.41
Pillar 6: Pioglitazone (PPAR-gamma agonist) Pioglitazone can improve insulin sensitivity partly by redistributing fat away from ectopic depots (liver and muscle) towards safer subcutaneous stores
Testosterone suppression of the HPT axis
