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Additionally, GIP receptor expression in hypothalamic regions and oligodendrocytes suggests central nervous system actions that may synergize with GLP-1 to reduce appetite and food intake while potentially mitigating GLP-1-associated nausea, thereby improving treatment tolerability [36,41,42]

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JAMA Network+3MDPI+3ScienceDirect+3 Why Alzheimers has been called type 3 diabetes For more than a decade, researchers have observed that insulin signaling in the brain is impaired in Alzheimers disease (AD)