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Risk factors include acute illness, reduced food intake, alcohol excess, and insulin dose reduction

Association of mildly reduced kidney function with cardiovascular disease: The Framingham heart study
Body composition analysis revealed that much of this loss came from fat mass rather than muscle, a crucial distinction for sustainable weight management
In two phase 3 clinical trials, retatrutide, a novel glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide 1 (GLP-1), and glucagon triple-hormone receptor agonist, demonstrated significant weight loss and clinically meaningful improvements in health outcomes in people living with obesity and type 2 diabetes
