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Yi B, Hu X, Wen Z, Zhang T, Cai Y

149151 These receptors each have independent yet complementary roles in the treatment of diabetes and obesity

Lancet 1998;352:854-865

Reference: Huang H et al

Two common adjustments include stepping down, where the dose is gradually lowered while monitoring for cravings, or stretching out, which involves extending the time between doses (e.g., moving from weekly to every 1014 days)
