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These comments are based primarily on research in rats who were administered GLP-1s and developed thyroid cancer

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Tolerance and response: a provider adjusts based on how a patient actually responds over time, which no static number can anticipate

Show Highlights & Big Takeaways Retatrutide is More Powerful, But Not Dramatically (Yet): While it works on three pathways and may lead to greater weight loss, current data shows only about a 23% improvement over Ozempic, not the massive difference often advertised

Rodbard HW, Rosenstock J, Canani LH, Deerochanawong C, Gumprecht J, Lindberg S, et al
