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Description
Diabetes 2025;74(Supplement_1):1966-LB Consultado el 29 de enero de 2026: Associations of semaglutide with incidence and recurrence of alcohol use disorder in real-world population Nat Commun 15, 4548 (2024)

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FIGURE 4 Further analysis of the trajectory suggests that the several important amino acids, such as H7, E9, T11, F12, D15, and F28 of GLP-1 actively interact with the W 39 , Y 145 , Y 152 , R 190 , K 197 , L 201 , N 300 , R 310 , E 364 , L 384 , and L 388 of GLP-1R through several hydrogen, hydrophobic, and electrostatic interactions (Figure 5
)
Griffin ME, Espinosa J, Becker JL, et al
showed that TZP in diabetic patients resulted in substantially greater GC and WL versus dulaglutide
