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A small human proof-of-concept trial reported that semaglutide reduced vastus lateralis cross-sectional area but did not reduce knee-extension strength or grip strength over 12 weeks

Discover how GLP-1 receptor agonists like semaglutide may reduce inflammation beyond blood sugar control

Id also raise the question of whether the incretins and other GLP-1 agonists will ever be free of adverse GI symptoms, as it seems intrinsic to the drugs mechanism.