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Over 250 patients underwent metabolomics and lipidomic investigations, which revealed that unlike the baseline and placebo, tirzepatide, taken over 26 weeks, significantly impacted a group of lipids and metabolites like 3-hydroxybutyrate reduced branched-chain ketoacids (BCKA), branched-chain amino acids (BCAA), and direct catabolic products linked with obesity and insulin resistance

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If you have a BMI of 28 and have been diagnosed with hypertension, for example, youd typically meet prescribing criteria

[DOI] [PubMed] [Google Scholar] Wolff M
Always seek treatment through regulated NHS or private healthcare providers where proper monitoring and follow-up can be ensured