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In addition, activating GLP-1R reduced Iba-1, IL-1 and TNF- release and inhibited TNC microglial number and morphological changes (process retraction) following nitroglycerin administration

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GLP-1RAs may be a practical, adjunctive treatment option for patients with psoriasis and metabolic comorbidities.

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), initially developed for the treatment of type 2 diabetes and obesity, may modulate pathways associated with the hallmarks of aging
