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Food and Drug Administration approved the use of liraglutide for obese children between ages 12 and 17, and it approved the use of semaglutide in 2022

In these cases, moving to a higher dose like 5 mg or 7.5 mg could potentially cause too much weight loss too quickly or lead to unnecessary side effects
The backing layer was made of the same PVA-PVP mixture but without metformin
The SURMOUNT trials, which evaluated tirzepatide for weight management, enrolled patients on strict seven-day schedules
A 2025 Cochrane review of 18 studies confirmed that semaglutide (Wegovy/Ozempic) results in approximately 10.7% greater weight loss compared to placebo, with high-certainty evidence [6]
