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Description
The US Food & Drug Administration (FDA) removed tirzepatidethe active ingredient in the weight loss drug Zepbound from its shortage list last year
Consequently, several therapeutic approaches have aimed to antagonize GCG activity in the management of T2DM
GLP1-RA treatment is associated with large reductions in both visceral and subcutaneous adipose tissue 51
Obesity is a common and serious disease
The SURMOUNT-1 study was a placebo-controlled 72-week trial in obese subjects that randomized 2,539 participants without diabetes into four equally large study arms with placebo or one of the three tirzepatide doses (5, 10, or 15 mg once weekly)
