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Initially, with weight loss, when you significantly decrease energy intake, the body will get energy needs through other sources such as glycogen

A paper published in early 2026 reviewed 12 clinical trials that had incorporated nutritional interventions or dietary assessments during semaglutide or tirzepatide therapy in adults with obesity or Type 2 diabetes

Its not a replacement for anything but a return to balance

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Conclusions The present updated meta-analysis of randomised clinical trials demonstrated that the use of semaglutide was associated with a marked anti-inflammatory effect