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[1] [3] GLP-1 plays a crucial role in glucose homeostasis and appetite regulation through multiple physiological pathways
Semaglutide (SUSTAIN and PIONEER) reduces cardiovascular events in type 2 diabetes across varying cardiovascular risk
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In 2014, they reported a tri-agonist targeting GLP-1R/GIPR/GCGR , demonstrating superior efficacy in mouse experiments [11]
