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At week 72, primary endpoints showed 62.9% of people treated with 2.4 mg semaglutide achieved resolution of steatohepatitis with no worsening of liver fibrosis compared to 34.1% on placebo

It slows bacterial growth rather than eliminating it entirely, and it does nothing to prevent the introduction of endotoxins or other non-living contaminants

The 39-amino-acid chain includes a C20 fatty diacid moiety that enables albumin binding and extends the half-life in the body, but this fatty acid component also creates additional degradation vulnerability in solution
doi: 10.1161/01.cir.0000437739.71477.ee 7

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