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Kim JK, Kim JY, Lee SM, et al

Caffeine (10 mg/kg/day, p.o.) and coffee (caffeine dose 286 mg/kg/day, p.o.) treatments were started at the second day of STZ-induced diabetes and performed for 7 weeks in male rats

In an ideal world, the need for such drugs would be reduced by population-based preventive strategies that reverse the upward shift in the population distribution of body mass index/body fat percentage. Unlike individual treatments, policy-level interventions need less personal effort and tend to reduce rather than increase health inequalities

In terms of administration , Mounjaro is given once weekly, similar to semaglutide and dulaglutide, which offers convenience compared to daily injections like liraglutide

Best Practice & Research Clinical Endocrinology & Metabolism, 30 (5), 555-567