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Once the 28-day window closes, any remaining medication should be discarded safely

Put ice packs around the carton but not in direct contact with the pen surface, as direct contact can freeze and damage the medication

When administered as a once-weekly subcutaneous injection, tirzepatide binds to both GIP and GLP-1 receptors, triggering multiple metabolic effects throughout the body

Medicare is also expanding access through the Medicare GLP-1 Bridge program, beginning July 1, 2026, for eligible Medicare Part D beneficiaries

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