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Those seeking weight management as a primary objective should discuss appropriate treatment options, including whether higher-dose semaglutide (Wegovy) or alternative interventions might be suitable, with their GP or specialist

Generic Alternatives While semaglutide itself does not have a generic equivalent, discussing other GLP-1 receptor agonists that are less expensive with your healthcare provider could be a viable option

A search of the trial literature and registries finds retatrutide studied in obesity, in type 2 diabetes, in MASLD, in knee osteoarthritis with obesity, and in cardiovascular-disease populations but not in a cohort defined by PCOS, and not with PCOS-specific reproductive or androgen endpoints