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A recent prospective study, which analyzed data from 237 patients with T2D, followed by nearly 5 years with elastography, suggested that SGLT2 inhibitors reduced the risk of worsening liver stiffness [102]

Interestingly, the GLP-1 receptor agonist, dulaglutide, and the dual GLP-1 and GIP receptor agonist, tirzepatide, are both characterized by a strong delayed gastric emptying upon a single dose administration, but the effect tends to subside as gastric emptying tachyphylaxis is observed after several weeks of treatment

Specifically, the guidance suggested withholding daily GLP-1RAs for one day and weekly formulations for one week prior to the date of the elective procedure

Bottom line: MeAgain connects food, protein, fiber, water, symptoms, and dose context inside the GLP-1 journey