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The next most common abnormality is maternal disomy 15, found in around 35% of cases, and a defect in the imprinting center that controls the activity of certain genes on chromosome 15, seen in 1-3% of cases

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USA 117 , 74617470 (2020)

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Achieving QW dosing in a small molecule requires extensive multi-parameter optimization to ensure sustained exposure and efficacy while minimizing side effectsa challenge perfectly suited for the battle tested generative AI

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