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One study showed an average weight loss of 27.3 lbs
[DOI] [PMC free article] [PubMed] [Google Scholar] 134.Tong, J

10.1016/j.ijcard.2018.12.005 51 SukumaranV.TsuchimochiH.SonobeT.WaddinghamM

Lean Mass Preservation: The Non-Negotiable Preserve Phase Lean mass preservation is essential during midlife GLP-1 therapy because estrogen decline already accelerates muscle loss

Many patients can lose a substantial amount of weight often 10% or more of their body weight in a year which can improve diabetes control and other health markers
