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reduced form)-dependent buffering systems, several constraint-sensitive metabolic processesincluding NAD partitioning, amino aciddependent antioxidantanabolic coupling, micronutrient-dependent enzymatic activity, and bile acidmediated absorptionmay become functionally limiting

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Although glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have been used as anti-obesity agents, there are individual differences between these agents, thus making it difficult to achieve optimal treatment efficacy

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