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The first one is metabolic decompensation in infancy (3 months to 2 years) with episodes of hypoketotic hypoglycaemia, hepatomegaly, lethargy, feeding difficulties, elevated hepatic aminotransferase levels and hypoammonemia (induced by fasting or illness, among other things)

Your healthcare provider can help you choose a target, but a common starting point is cutting about 500 calories per day

The proposed mechanisms include GLP-1 mediated changes in blood pressure regulation, effects on retinal and optic nerve blood flow, and potential interactions with cardiovascular risk factors that are common in the populations taking these drugs

Beyond just aesthetics, muscle wasting can lead to reduced strength, a higher risk of injury, and a decline in overall physical function

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