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Mechanism of action of trizepatide is presented in Figure 4

This triple activation creates a synergistic effect that surpasses what single or dual agonists can achieve

Retrospective cohort studies suggest that the use of GLP-1 medicines is associated with improved inflammatory bowel disease outcomes in people with T2D (83, 84)

PMC (National Institutes of Health)

Specialist diabetes services will conduct a thorough assessment, including: Review of your diabetes history and current medications Assessment of cardiovascular risk factors Evaluation of potential contraindications and precautions Discussion of treatment goals, including weight management Education on injection technique (for injectable formulations) Monitoring plan for efficacy and tolerability NICE recommends that GLP-1 therapy should be reviewed at six months