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WARNING Please contact your doctor ASAP and seek in-person care immediately if a side effect becomes problematic or you experience: Severe nausea and/or vomiting resulting in dehydration: It is important to stay well hydrated and drink plenty of fluids while on this medication Kidney problems/kidney failure: Vomiting, nausea, diarrhea can cause dehydration and kidney issues and make kidney problems worse in individuals who have pre-existing kidney conditions

Common Mistakes During Reconstitution Using tap water instead of bacteriostatic water Applying vigorous shaking instead of gentle swirling Failing to refrigerate the reconstituted solution Not labeling the vial with concentration or date Over-diluting or under-diluting the peptide solution Each of these errors can lead to inaccurate concentration, reduced peptide stability, or contamination

While GIPR antagonism has only little effects to decrease body weight in DIO mice (181, 183186), its combination with GLP-1R agonism decreases body weight beyond what is possible with either monotherapy alone (181)

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