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Although our primary analyses focused on AOM tirzepatide and AOM semaglutide, we extracted dispense data for all GLP-1 RAs to examine overall treatment transitions and identify which therapies patients switched to

[The mediation analysis] suggests that other direct effects of tirzepatide on the leakage of albumin through the glomeruli are involved as well, Heerspink said

These encompass nuclear hormone receptor agonists, fibroblast growth factors 19 and 21, incretins (single, dual, or triple), sodium-glucose cotransporter inhibitors, and agents modulating metabolic pathways

Women with PCOS seeking fertility should follow established treatment guidelines including lifestyle modification and ovulation induction medications like letrozole

Sparks, M