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Retatrutide (LY3437943) is an investigational triple agonist targeting GIP, GLP-1, and glucagon receptors, currently under clinical evaluation for obesity and metabolic disease
This is likely due to greater weight loss seen in this trial, approximately 21% with 15 mg dosing, far exceeding the 14% weight loss observed in GLP-1 RA trials [14, 16, 19, 20, 23]

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The results broaden the scope of possibility for treating and potentially curing rheumatoid arthritis and other autoimmune diseases.
