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Further, we found a decrease in TKV in all active treatment groups, which was possibly mediated by a reduction in hyperfiltration

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These class of drugs are Glucagon-Like-Peptide-1 agonists, and mimic and enhance the effect of the naturally occurring hormone GLP-1 in the body.

CagriSema combines cagrilintide with semaglutide and is studied in Novo Nordisk's REDEFINE obesity trials

FDA-approved semaglutide products (Ozempic, Wegovy, Rybelsus) are commercially available