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Many claims focus on digestive injuries tied to slow gastric emptying, including persistent vomiting, inability to tolerate meals, and findings of undigested food in the stomach on imaging or endoscopy

This analysis also indicated that sitagliptin was the only DPP-4 inhibitor that improved insulin resistance when used as monotherapy

It also carries a black box warning for increased suicidal thoughts in young adults, consistent with other antidepressants

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