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As the majority of patients with T2DM are also obese, medications that exacerbate weight gain are not ideal

Understanding the side effects of semaglutide and tirzepatide: A comprehensive guide for patients

Moreover, a significant rise in fasting levels of adiponectin by 1226% and IGF binding proteins IGFBP-1 and IGFBP-2, markers of insulin sensitivity, were reported following treatment with all doses of tirzepatide [74]

However, some clinicians and researchers are beginning to explore whether metabolic therapies could influence the disease

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