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Description

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Last month, Novo Nordisk won Food and Drug Administration approval for the first GLP-1 pill for weight loss

A game-changer in obesity treatment Initially developed for type 2 diabetes, GLP-1 receptor agonists work by mimicking hormones in the gut to regulate blood sugar levels and appetite

This is complemented by the incretin effect, insulin-sensitising properties, and promotion of subcutaneous fat accumulation mediated by GIP, as well as the thermogenic and lipolytic actions of GCG (Table 2).54 Its structure resists degradation by DPP-4 and enables binding to albumin, resulting in a half-life of six days, which allows for once-weekly subcutaneous administration