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95,116 Beyond mitochondria and the NOX family, a variety of enzymes including xanthine oxidase (XO), NOS, lipoxygenase and cytochromes P450 (CYP) can all produce ROS using NAD(P)H as electron donor
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The additive effect appears strongest in individuals with insulin resistance, where metformin's mechanism directly addresses a core metabolic defect
The biggest promise of the grapefruit diet is significant weight loss in a short period of time
