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Examples of side effects that have been reported with both drugs include: constipation diarrhea nausea and vomiting abdominal pain indigestion (upset stomach) gas acid reflux injection site reactions reduced appetite severe nausea, vomiting, or diarrhea that may lead to dehydration and kidney problems gallbladder problems, such as gallstones pancreatitis (swelling in your pancreas) low blood sugar (mainly in people also taking insulin or certain other diabetes medications) boxed warning: risk of thyroid cancer Allergic reactions were reported in clinical studies of Mounjaro

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Exclusion criteria included less than 3 months of semaglutide use, history of bariatric surgery, and active malignancy

Subcutaneous fat pads in the cheeks, temples, and under the eyes act as natural scaffolding