indications for glp 1 agonists The expanding role of GLP-1 receptor agonists: a narrative review of current evidence and future directions The Role of Glucagon-Like Peptide-1

40 Preclinical studies have shown that these effects are mainly mediated trough the effects of GLP-1R activation in the central nervous system (CNS) by the modulation of orexigenic and anorexigenic signaling pathways

Therefore, women of childbearing age should be advised that significant weight loss may increase fertility, requiring effective contraception

10.1002/oby.70024

[DOI] [PubMed] [Google Scholar] 56.Quddos F, Hubshman Z, Tegge A, Sane D, Marti E, Kablinger AS, et al

Their smaller molecular structure also facilitates better tissue penetration and lower production costs, which could enhance accessibility to these novel medications